23. Intracranial hypertension secondary to levofloxacin-therapy

Article type: Teaching Images
Article title: Intracranial hypertension secondary to levofloxacin-therapy

Journal: Archives of Medicine and Health Sciences
Year: 2019
Authors: Jamir Pitton Rissardo, Ana Letícia Fornari Caprara
E-mail: jamirrissardo@gmail.com

ABSTRACT
Idiopathic intracranial hypertension (ICH) is characterized by elevated intracranial pressure without an evident etiology. Here, we report the case of an adult male who presented with headache, diplopia, blurred vision, and nausea. The patient stated that he had searched a general practitioner 1 week ago because he had experienced cough, dyspnea, and fever. The physician started levofloxacin. On admission, the patient reported that his respiratory symptoms recovered. However, he complained about the beginning of neurological symptoms. On neurological examination, papilledema and unilateral abducens weakness were observed. Brain magnetic resonance imaging showed radiographic features of ICH. A lumbar puncture had an opening pressure of 50 cmH2O. Levofloxacin was withdrawn, and acetazolamide 250 mg bid was started. After 2 weeks, the patient had full recovery of the symptoms, and 4 weeks later, no papilledema was observed.
Keywords: Headache, intracranial hypertension, levofloxacin, quinolones

Full text available at:

DOI
10.4103/amhs.amhs_118_19

Citation
Rissardo JP, Caprara AL. Intracranial hypertension secondary to levofloxacin-therapy. Arch Med Health Sci 2019;7:313-6