26. Carbamazepine-associated urinary incontinence: a case report and literature review

Article type: Case Report                                                                                         
Article title: Carbamazepine-associated urinary incontinence: a case report and literature review

Journal: International Journal of Medicine and Health Development
Year: 2019
Authors: Jamir Pitton Rissardo, Ana Letícia Fornari Caprara
E-mail: jamirrissardo@gmail.com

ABSTRACT
Carbamazepine (CBZ) is an anticonvulsant approved for the management of many neurological and psychiatric disorders. We present a case of an adult male with epilepsy who reported new seizures, and the dose of CBZ administered was 1600 mg daily. CBZ dose was increased to 1800 mg daily. The subject complained of urinary incontinence without dysuria that started after the CBZ dose increase. It was associated with urgency, hesitancy, dribbling of urine, and poor stream. Laboratory tests were within normal limits. He admitted dry mouth, flushing, constipation, and accommodation paralysis starting after CBZ increase. Assuming that these symptoms were an adverse drug reaction, CBZ was withdrawn and valproate was started. The individual had full recovery within four weeks. To the best of our knowledge, only two case reports of similar nature are available, but this is the first one to be reported with a young male adult.
Keywords: Carbamazepine, anticonvulsant, urinary incontinence

Full text available at:

DOI
10.4103/ijmh.IJMH_25_19

Citation
Rissardo JP, Caprara AL. Carbamazepine-associated urinary incontinence: a case report and literature review. Int J Med Health Dev 2019;24:114-7