Article type: Case Report
Article
title: Oromandibular dystonia secondary to methylphenidate: a case report and literature review
Journal: International
Archives of Health Sciences
Year: 2020
Authors: Jamir Pitton Rissardo, Ana Letícia Fornari
Caprara
E-mail: jamirrissardo@gmail.com
ABSTRACT
Methylphenidate
(MTP) is a first-line treatment for attention-deficit hyperactivity disorder
(ADHD) in children and adults and as a second-line treatment for narcolepsy in
adults. We report a case of a young adult male who presented with abnormal
orofacial movements after MTP use for the management of ADHD. Laboratory tests
were within normal limits. His family history was unremarkable and negative for
neurological diseases. A dose of MTP was given during the neurological
examination, and abnormal facial movements suggestive of oromandibular dystonia
(DTN) were observed. MTP was withdrawn and the symptoms recovered. The
oromandibular DTN secondary to MTP probably occurs due to influences in the
dopaminergic pathway, and these dyskinetic movements may be associated with a
disbalance state of the dopamine, in which an increase or decrease of this
neurotransmitter could lead to abnormal movements.
Key-words: Dystonia, methylphenidate, oromandibular
dystonia, tongue movements
Full text available at:
DOI
10.4103/iahs.iahs_71_19
Citation
Rissardo JP, Caprara AL. Oromandibular
dystonia secondary to methylphenidate: a case report and literature review. Int Arch Health Sci 2020;7:108-11.
