117. The unknown etiology of new-onset refractory status epilepticus

Article type: Letter to Editor                                                                                    

Article title: The unknown etiology of new-onset refractory status epilepticus

 

Journal: Current Medical Issues

Year: 2022

Authors: Jamir Pitton Rissardo, Ana Letícia Fornari Caprara

E-mail: jamirrissardo@gmail.com

 

ABSTRACT

New-onset refractory status epilepticus (NORSE) was first reported by Einar P Wilder-Smith in 2005. This term refers to individuals with super refractory status epilepticus without associated past medical history of epilepsy and with no identifiable cause despite initial evaluation. About half of patients with NORSE have an unknown etiology despite an extensive workup. However, a recent systematic review of the literature further “entangled” this mystery. Herein, we would to discuss the possible etiologies of NORSE. Lattanzi et al. studied 197 records with 1334 patients both pediatric and adult. We reanalyzed their spreadsheet database and supplementary material to better describe the following question “What is the etiology of NORSE?”

Keywords: Norse, etiology, status epilepticus, epilepsy, encephalitis

 

Full text available at:

https://www.cmijournal.org/article.asp?issn=0973-4651;year=2022;volume=20;issue=2;spage=119;epage=120;aulast=Rissardo

 

DOI

10.4103/cmi.cmi_5_22

 

Citation

Rissardo JP, Caprara AL. The unknown etiology of new-onset refractory status epilepticus. Curr Med Issues 2022;20:119-20