60. Pourfour du Petit Syndrome

Pourfour du Petit Syndrome
The reverse Horner syndrome!
François Pourfour du Petit (1664–1741)
- 1st to describe

2) Definition
“ipsilateral mydriasis, hyperhidrosis, and eyelid retraction”

3) Pathophysiology
"oculosympathetic chain irritation causing the clinical signs of hyperactivity of the sympathetic pathway"
- causes are the same as those for Horner syndrome

4) Management
- resolve spontaneously
- clonidine
- sympathectomy

5) PPS cases
5.1 PPS associated with a cervical vertebral anomaly
- noticed at physical exercise (2 floors of stairs, two times, an go..)
5.2. PPS

5.3. PPS associated with internal carotid artery dissection
- hyperhidrosis
- eyelid retraction
- Fig b shows improvement after botox

5.4. Horner syndrome & Pourfour du Petit syndrome associated with oesophagostomy tube placement in a cat
First developed Horner syndrome (a); Later, Pourfour du Petit syndrome (b)

5.5. PPS after medullary thyroid carcinoma surgery
A) Day 5 after thyroid surgery, with right mydriasis and ipsilateral upper eyelid retraction. 
B) Follow-up 2 months after thyroid surgery, with complete resolution

5.6. PPS associated with thyroid CA

5.7. PPS due to ipsilateral IJV distention

5.8. PPS associated with cluster headache