Blood pressure in acute stroke
What is the optimal blood pressure after EVT?
BP & stroke
- high BP: inc risk of ICH and cerebral edema
- low BP: dec perfusion in vulnerable ischemic areas
Clinical trials
BP-TARGET trial
- intense versus standard BP
- did not improve outcome
ENCHANTED 2 trial
- intense versus standard BP
- worsened functional outcome
OPTIMAL-BP
- intense versus standard
- worsened functional outcome
BEST-II
- intense versus standard
- no diference
CLEVER
- clevidipine is safe to use EVT
