Clinical trial - endovascular thrombectomy
Trials
Timing
Extended window
DAWN (2018)
- EVT 6-24 h after stroke w/ mismatch
- EVT better functional outcome
DIFFUSE 3 (2018)
- EVT 6-16 h after stroke w/ mismatch
- EVT better functional outcome
Early window
MR CLEAN (2015)
EXTENDED-IA (2015)
ESCAPE (2015)
SWIFT PRIME (2015)
- EVT < 6h
- EVT better functional outcome
Large core
RESCUE-Japan LIMIT (2022)
ANGEL-ASPECT (2023)
- EVT better functional outcome
- inc ICH %
SELECT2 (2023)
TENSION (2023)
- EVT better functional outcome
- same ICH %
TESLA (2024)
LASTE (2024)
- same functional outcome
Additional thrombolytic
DIRECT-MT (2020)
- EVT w/ & w/o tPA has no significant difference
MR CLEAN-NO IV (2021)
- EVT w/ & w/o tPA has no significant difference
Low NIHSS
MOSTE
- determine MT efficacy and safety in patients with minor stroke and LVO in the anterior circulation; NIHSS score ⩽ 5
Large Bore
C-92
- cereglide device
- large bore better functional outcome
SUMMIT MAX
- HiPoint device
- similar outcome
