Article type: Literature Review
Article title: Understanding Reflex Epilepsy: Triggers, Mechanisms, And Management
Journal: IJMSDH
Year: 2025
Authors: Faiyyaz Ur Rehman, Jamir Pitton Rissardo, Nigar Hashmi, Han Gul, And Ana LetÃcia Fornari Caprara
E-mail: jamirrissardo@gmail.com
ABSTRACT
Reflex epilepsy, a distinctive subset of epileptic disorders, is characterized by seizures reliably triggered by specific stimuli or activities. This comprehensive literature review synthesizes current knowledge and recent advancements in understanding reflex epilepsy, shedding light on its diverse triggers, clinical manifestations, and underlying neurophysiological mechanisms. The review explores the vast array of triggers, encompassing visual stimuli, specific movements, cognitive processes, and sensory inputs, revealing the intricate interplay between external stimuli and epileptic events. Significant clinical heterogeneity is observed in reflex epilepsy, with manifestations ranging from focal motor seizures to alterations in consciousness. Advances in neuroimaging and electroencephalography have contributed valuable insights into the neurophysiological basis of reflex epilepsy, emphasizing cortical hyperexcitability and abnormalities in sensory and cognitive processing. Genetic and molecular studies have uncovered potential markers associated with reflex epilepsy, offering a glimpse into its hereditary aspects and paving the way for future diagnostic and therapeutic strategies. The literature underscores the psychosocial impact of reflex epilepsy on the quality of life of affected individuals, prompting the need for holistic, patient-centered care approaches.
Keywords: reflex epilepsy, triggers, seizure, musicogenic epilepsy, reflex, photosensitivity.
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Citation
Rehman FU, Rissardo JP, Hashmi N, Gul H, Caprara ALF. Understanding Reflex Epilepsy: Triggers, Mechanisms, And Management. IJMSDH 2025;11:01-19.
Figure 1. Prevalence of Different Types of Reflex Epilepsy.