Restless legs syndrome
- Start w/ gabapentin enacarbil (Horizant) > gabapentin > pregabalin
- IV iron: ferric carboxymaltose > low molecular weight iron dextran > ferumoxytol > ferrous sulfate
- Others: dipyridamole, extended-release oxycodone
- Devices: Nidra (bl high-frequency peroneal nerve stimulation)
- Against: levodopa, pramipexole, transdermal rotigotine, bupropion, carbamazepine, clonazepam, valerian, valproic acid, cabergoline
- IV iron: ferric carboxymaltose > low molecular weight iron dextran > ferumoxytol > ferrous sulfate
- Others: dipyridamole, extended-release oxycodone
- Devices: Nidra (bl high-frequency peroneal nerve stimulation)
- Against: levodopa, pramipexole, transdermal rotigotine, bupropion, carbamazepine, clonazepam, valerian, valproic acid, cabergoline
> if needs a dopamine agonist, consider Neupro (transdermal rotigotine)
- special situations:
> ESRD, consider vitamin C
> PLMD: against triazolam, VPA
