Stroke - Hypercoagulability work-up

Hypercoagulable panel

Basic
- PTT
- thrombin time
- fibrinogen

Antithrombin III
- antithrombin III activity

Protein C & S
- protein C
- APC resistance (activated protein C resistance)
- protein S

APLS
- hexagonal antibody (hexagonal phase phospholipid neutralization)
- cardiolipin antibody (IgG, IgA, IgM)
- B2-glycoprotein antibody
- DRVVT screen (to detect lupus anticoagulant)
> dilute Russell viper venom

Genetics
- Factor V Leiden mutation
- Factor II (prothrombin) mutation

Others
Less commonly ordered tests
- D-dimer
- lipoprotein (a)
- homocysteine
- factor VIII activity
- MTHFR mutation