Direct-to-Angio - Clinical trials
Basics
-Test workflow speed
(🚑 → Angio) vs (🚑 → ED → CT → decision → Angio)
-Goal: ⬇️ Door-to-puncture time→ improve outcomes (time-dependent EVT benefit)
Trials
Pfaff et al. (2020)
↓ DTP time, no fx benefit
ANGIOCAT (2021)
↓ DTP, improved fx outcome
DIRECT ANGIO (2026)
↓ DTP, no fx benefit
↑ ICH (safety sign)→ Stopped early (methodologic concerns)
DIRECT (Ongoing)
Cooper is a center