Ataxia Phenomenology Atlas (Part 3): Immune-Mediated, Paraneoplastic and Inflammatory Ataxias
Alexander Disease
Video 13.46 (C13c46): Adult-Onset Alexander Disease
Palatal myoclonus, mild cerebellar ataxia, and the characteristic MRI “tadpole sign.”
CANVAS
Video 13.47 (C13c47): CANVAS (Cerebellar Ataxia, Neuropathy, Vestibular Areflexia Syndrome)
Chronic cough, vestibular areflexia, sensory ataxia, and visual compensation during gait.
Post-Infectious and Autoimmune Ataxias
Video 13.49 (C13c49): Post-Infectious Cerebellitis with Myoclonus
Positive and negative myoclonus superimposed on mild cerebellar ataxia.
Video 13.50 (C13c50): Post-Infectious Opsoclonus-Myoclonus-Ataxia Syndrome (OMAS)
Opsoclonus, action myoclonus, and ataxia resolving with immunotherapy.
Video 13.51 (C13c51): Anti-GAD Cerebellar Ataxia
Progressive scanning dysarthria and severe gait instability.
Video 13.52 (C13c52): Advanced Anti-GAD Cerebellar Ataxia
Severe appendicular and gait ataxia with inability to stand independently.
Video 13.53 (C13c53): Para-Infectious OMAS
Florid opsoclonus, myoclonus, and ataxia with complete treatment response.
Video 13.54 (C13c54): Post-COVID OMAS
Ocular flutter, mild myoclonus, and cerebellar gait ataxia.
Video 13.55 (C13c55): Para-Infectious OMAS (Recovery Phase)
Resolving ocular flutter, action myoclonus, and gait instability.
Paraneoplastic Cerebellar Syndromes
Video 13.56 (C13c56): Anti-Yo Cerebellar Degeneration
Scanning dysarthria, tremor, dysmetria, and severe gait ataxia.
Video 13.57 (C13c57): Advanced Anti-Yo Cerebellar Degeneration
Head tremor, severe cerebellar dysarthria, and appendicular ataxia.
Video 13.58 (C13c58): Paraneoplastic Cerebellar Degeneration
Severe titubation, cerebellar tremor, and inability to ambulate independently.
Video 13.59 (C13c59): Cerebellar (Holmes-Type) Tremor in Paraneoplastic Disease
Severe unilateral proximal tremor with marked target impairment.