Chorea Phenomenology Atlas (Part 1): Early and Moderate Huntington Disease
Video 11.1 (C11c1): Early Huntington Disease
Mild generalized chorea, motor impersistence, blink-assisted saccades, and genetically confirmed HD (42 CAG repeats).
Video 11.2 (C11c2): Very Early Huntington Disease
Subtle distal chorea activated by concentration with minimal neurological impairment.
Video 11.3 (C11c3): Huntington Disease Mimicking Cerebral Palsy
Dystonic choreoathetosis, pseudobulbar speech, and positive HD genetic testing (43 CAG repeats).
Video 11.4 (C11c4): Mild to Moderate Huntington Disease
Generalized chorea, head-thrust saccades, motor impersistence, and gait instability.
Video 11.5 (C11c5): Mild Huntington Disease
Subtle facial and distal limb chorea with otherwise preserved neurologic function.
Video 11.6 (C11c6): Early Huntington Disease with Retro-Arm Swing
Mild generalized chorea and characteristic posterior arm displacement during gait.
Video 11.7 (C11c7): Early Huntington Disease with Behavioral Features
Mild chorea and emerging irritability responsive to olanzapine.
Video 11.8 (C11c8): Mild Huntington Disease (39 CAG Repeats)
Generalized chorea with motor impersistence and preserved long-term function.
Video 11.9 (C11c9): Huntington Disease with Behavioral Disinhibition
Generalized chorea and later development of socially disruptive vocal behaviors.
Video 11.10 (C11c10): Huntington Disease with Emotional Lability
Generalized chorea, motor impersistence, and mild gait dysfunction.
Video 11.11 (C11c11): Moderate Huntington Disease
Prominent generalized chorea causing impaired balance and improved by olanzapine.
Video 11.12 (C11c12): Reduced-Penetrance Huntington Disease
Mild generalized chorea with 33 CAG repeats and response to valbenazine.
Video 11.13 (C11c13): Impulsive Huntington Disease
Moderate generalized chorea with behavioral impulsivity and activation by movement.
Video 11.14 (C11c14): Huntington Disease with Oculomotor Dysfunction
Generalized chorea, motor impersistence, impaired vertical saccadic initiation, and gait instability.
Video 11.15 (C11c15): Moderate Huntington Disease with Dysarthria
Continuous chorea, slowed saccades, dysarthria, and impaired coordination.
Video 11.16 (C11c16): Severe Choreic Huntington Disease
Profound generalized chorea causing major gait and balance disability.
Video 11.17 (C11c17): Huntington Disease with Falls and Subdural Hematomas
Mild chorea associated with recurrent falls and significant intracranial injury.
Video 11.18 (C11c18): Huntington Disease with Cognitive and Affective Changes
Prominent chorea, apathy, motor impersistence, and 51 CAG repeats.
Video 11.19 (C11c19): Mild Huntington Disease Responsive to Olanzapine
Generalized chorea and balance impairment improved with treatment.
Video 11.20 (C11c20): Huntington Disease Treated with Valbenazine
Moderate chorea causing gait instability with symptomatic improvement on VMAT2 inhibition.