Article type: Case Report
Article
title: Isolated
acute pseudobulbar palsy with infarction of artery of percheron: case report
and literature review
Journal: African
Health Sciences
Year: 2021
Authors: Jamir Pitton Rissardo, Ana Letícia Fornari
Caprara
E-mail:
jamirrissardo@gmail.com
ABSTRACT
Introduction: Pseudobulbar palsy (PBP) is
characterized by supranuclear lesions in the corticobulbar pathway. Neoplasia,
inflammatory, demyelinating, and stroke are possible etiologies of this
disorder. Case report: We report an elderly female who presented with
dysarthria. She was dysarthric with a hypernasal voice, no apraxia or aphasia
was observed. Tongue movements were slow with limited amplitude. Her soft
palate dropped bilaterally; gag reflex was present. Also, she reported
swallowing difficulty and choking with her saliva. Bilateral vertical and
horizontal gaze were intact to either voluntary or oculocephalic movements. A
cranial CT scan was suggestive of artery of Percheron (AOP) infarction. Brain
magnetic resonance imaging showed hypersignal on diffusion-weighted and
T2-weighted images and hyposignal on apparent diffusion coefficient in both
thalami. CT angiography scan revealed an AOP originating from the left
posterior cerebral artery. The swallowing study with a videofluoroscopic
demonstrated oral and pharyngeal phases with severe dysfunction. Conclusion: To
the authors’ knowledge, there are two cases of individuals with artery of
Percheron infarction who devel- oped PBP associated with other clinical
syndromes. Still, isolated PBP following infarction of Percheron’s artery was
not reported. We hypothesized that the PBP may have occurred because of the
existence of vascular territory variations in the perforating arteries that
arise from the AOP.
Keywords: Pseudobulbar palsy, thalamus, infarction
Full text available at:
https://www.ajol.info/index.php/ahs/article/view/206045
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8356591/
DOI
10.4314/ahs.v21i1.22
Citation
Rissardo
JP, Caprara AL. Isolated acute pseudobulbar
palsy with infarction of artery of percheron: case report and literature review.
Afr Health Sci 2021;21:166-71
