Article type: Original Article
Article
title: Characteristics
of post-ictal headaches in patients with epilepsy: a longitudinal study
Journal: Seizure
Year: 2020
Authors: Jamir Pitton Rissardo, Ana Letícia Fornari
Caprara, Martim Tobias Bravo Leite, Juliana Oliveira Freitas Silveira, Paulo
Gilberto Medeiros Jauris, Josi Arend, Aline Kegler, Luiz Fernando Freire Royes,
Michele Rechia Fighera
E-mail: jamirrissardo@gmail.com
ABSTRACT
Objectives: This study aimed to investigate the
clinical predictors of post-ictal headache (PIH) in patients with epilepsy in a
tertiary center in Brazil. Methods: 302 individuals with adult-onset epilepsy
were followed for 9.8 years in our Hospital. Structured questionnaires about
headaches were applied. The presence of PIH was the primary outcome. We used
multilevel linear modeling in our data analysis. Results: From the total, 46.3%
had post-ictal headaches. Tension-type post-ictal headache was present in 55%
(N = 77) of the subjects, migrainous in 32.1% (N = 45), and both types in 12.8%
(N = 18). Family history of migraine (Odds ratio: 1.696; 95% CI: 1.372 to
2.096), diagnosis of drug-resistant epilepsy (Odds ratio: 1.169; 95% CI: 1.135
to 2.146), months since last visit (Odds ratio: 1.464; 95% CI: 1.243 to 2.888),
and generalized seizure onset type of epilepsy (Odds ratio: 1.527; 95% CI:
1.114 to 1.668), were significant determinants of PIH on multilevel linear
modeling. Discussion: PIH are associated with drug-resistant epilepsy,
generalized seizures, and family history of migraine. The rates of pos-ictal
headaches could be influenced by the use of antiepileptic drugs.
Keywords: Predictors, cephalgia, seizures,
cohort
Full text available at:
https://www.seizure-journal.com/article/S1059-1311(20)30237-5/
https://pubmed.ncbi.nlm.nih.gov/32896689/
DOI
10.1016/j.seizure.2020.08.001
Citation
Rissardo
JP, Caprara AL, Leite MT, Silveira JO, Jauris PG, Arend J, Kegler A, Royes LF, Fighera
MR. Characteristics of post-ictal headaches in patients with epilepsy:
a longitudinal study. Seizure 2020;81:244-49
