Article type: Letter to Editor
Article title: Risk factors for Parkinson’s disease dementia
Journal: Annals of Movement Disorders
Year: 2023
Authors: Jamir Pitton Rissardo, Ana Letícia Fornari Caprara
E-mail: jamirrissardo@gmail.com
ABSTRACT
Dementia affects >80% of the patients with Parkinson’s disease (PD). It is more common in patients with PD than in the general population. In addition, cognitive dysfunction is a crucial predictor of institutional placement in patients with PD. The institutionalization of patients with PD is related to worsening cognition, loss of decision-making capacity, and a poor patient-caregiver relationship. Furthermore, there are important concerns regarding the economic burden of the healthcare system and institutional placement.
Keywords: Dementia; cognitive impairment; risk factors; prognosis; parkinson’s disease
Full text available at:
DOI
10.4103/aomd.aomd_52_22
Citation
Rissardo JP, Caprara ALF. Risk factors for Parkinson’s disease dementia. Ann Mov Disord 2023;6:156-65.
Table 1. Risk Factors for Parkinson’s disease dementia and mild cognitive impairment reported in the literature.
Figure 1. Genetic basis of mild cognitive impairment and dementia in Parkinson’s disease. APOE, apolipoprotein E; COMT, catechol-O-methyltransferase; GBA, glucocerebrosidase; MAPT, microtubule-associated protein tau; SNCA, α-synuclein.